RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
let-7d
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
NA
Target
HMGA2
Pathway
NA
PubMed ID
Title
Let-7d miRNA prevents TGF-beta1-induced EMT and renal fibrogenesis through regulation of HMGA2 expression
Year
2016
Function
Hmga2 and let-7d miRNA significantly impact on the progression of TGF-beta-induced epithelial-mesenchymal transition (EMT) and fibrogenesis both in vitro and in vivo.